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Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe.

This report presents information on risk factors for oesophageal cancer in Bulawayo, Zimbabwe. The data analysed were from the Cancer Registry of Bulawayo for the years 1963-77, when all registered patients were interviewed using a standard questionnaire. The age-standardised incidence rates in the...

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Autores principales: Vizcaino, A. P., Parkin, D. M., Skinner, M. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033891/
https://www.ncbi.nlm.nih.gov/pubmed/7669592
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author Vizcaino, A. P.
Parkin, D. M.
Skinner, M. E.
author_facet Vizcaino, A. P.
Parkin, D. M.
Skinner, M. E.
author_sort Vizcaino, A. P.
collection PubMed
description This report presents information on risk factors for oesophageal cancer in Bulawayo, Zimbabwe. The data analysed were from the Cancer Registry of Bulawayo for the years 1963-77, when all registered patients were interviewed using a standard questionnaire. The age-standardised incidence rates in the urban population of Bulawayo in the first 10 year period were 58.6 per 100,000 in men and 8.1 in women. The distribution of risk factors was assessed in 881 oesophageal cancer cases (826 male, 55 female) and a control group comprising other non-tobacco- and non-alcohol-related cancer (5238) cases. There was a marked geographical gradient in risk in both sexes, which remained after adjustment for lifestyle variables. In men tobacco smoking was significantly associated with risk of oesophageal cancer, with the relative risk rising to 5.7 among smokers of 15 or more g day-1; this effect is independent of alcohol drinking. Among women who had ever smoked tobacco, the relative risk was 4.0 compared with those who had never smoked. Alcohol intake showed no independent effect on risk. Low socioeconomic status [odds ratio (OR) = 1.5; confidence interval (CI) = 1.0-2.1] and working as a miner (OR = 2.5; CI = 1.5-4.2) conferred increased risks in comparison with men of high socioeconomic status.
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spelling pubmed-20338912009-09-10 Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe. Vizcaino, A. P. Parkin, D. M. Skinner, M. E. Br J Cancer Research Article This report presents information on risk factors for oesophageal cancer in Bulawayo, Zimbabwe. The data analysed were from the Cancer Registry of Bulawayo for the years 1963-77, when all registered patients were interviewed using a standard questionnaire. The age-standardised incidence rates in the urban population of Bulawayo in the first 10 year period were 58.6 per 100,000 in men and 8.1 in women. The distribution of risk factors was assessed in 881 oesophageal cancer cases (826 male, 55 female) and a control group comprising other non-tobacco- and non-alcohol-related cancer (5238) cases. There was a marked geographical gradient in risk in both sexes, which remained after adjustment for lifestyle variables. In men tobacco smoking was significantly associated with risk of oesophageal cancer, with the relative risk rising to 5.7 among smokers of 15 or more g day-1; this effect is independent of alcohol drinking. Among women who had ever smoked tobacco, the relative risk was 4.0 compared with those who had never smoked. Alcohol intake showed no independent effect on risk. Low socioeconomic status [odds ratio (OR) = 1.5; confidence interval (CI) = 1.0-2.1] and working as a miner (OR = 2.5; CI = 1.5-4.2) conferred increased risks in comparison with men of high socioeconomic status. Nature Publishing Group 1995-09 /pmc/articles/PMC2033891/ /pubmed/7669592 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Vizcaino, A. P.
Parkin, D. M.
Skinner, M. E.
Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe.
title Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe.
title_full Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe.
title_fullStr Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe.
title_full_unstemmed Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe.
title_short Risk factors associated with oesophageal cancer in Bulawayo, Zimbabwe.
title_sort risk factors associated with oesophageal cancer in bulawayo, zimbabwe.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033891/
https://www.ncbi.nlm.nih.gov/pubmed/7669592
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