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High-dose interleukin 2 promotes bacterial translocation from the gut.

Toxicity associated with high-dose recombinant interleukin 2 (rIL-2) therapy simulates a sepsis syndrome, but the mechanism remains unclear. We hypothesised that translocated gut-origin bacteria may be important. Fifty-one male rats were randomised to receive rIL-2 by intraperitoneal injection at do...

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Detalles Bibliográficos
Autores principales:	Reynolds, J. V., Murchan, P., Leonard, N., Gough, D. B., Clarke, P., Keane, F. B., Tanner, W. A.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1995
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033909/ https://www.ncbi.nlm.nih.gov/pubmed/7669573

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