Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin.

Weekly treatments with doxorubicin encapsulated in long circulating, sterically stabilised liposomes (DOX-SL) reduced the incidence of metastases from primary mammary carcinoma from 24 of 47 untreated mice to 3 of 23 treated mice. Toxic side-effects were limited to minor, transient weight losses.

Detalles Bibliográficos
Autores principales: Vaage, J., Donovan, D., Loftus, T., Working, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033931/
https://www.ncbi.nlm.nih.gov/pubmed/7577449
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author Vaage, J.
Donovan, D.
Loftus, T.
Working, P.
author_facet Vaage, J.
Donovan, D.
Loftus, T.
Working, P.
author_sort Vaage, J.
collection PubMed
description Weekly treatments with doxorubicin encapsulated in long circulating, sterically stabilised liposomes (DOX-SL) reduced the incidence of metastases from primary mammary carcinoma from 24 of 47 untreated mice to 3 of 23 treated mice. Toxic side-effects were limited to minor, transient weight losses.
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spelling pubmed-20339312009-09-10 Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin. Vaage, J. Donovan, D. Loftus, T. Working, P. Br J Cancer Research Article Weekly treatments with doxorubicin encapsulated in long circulating, sterically stabilised liposomes (DOX-SL) reduced the incidence of metastases from primary mammary carcinoma from 24 of 47 untreated mice to 3 of 23 treated mice. Toxic side-effects were limited to minor, transient weight losses. Nature Publishing Group 1995-11 /pmc/articles/PMC2033931/ /pubmed/7577449 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Vaage, J.
Donovan, D.
Loftus, T.
Working, P.
Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin.
title Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin.
title_full Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin.
title_fullStr Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin.
title_full_unstemmed Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin.
title_short Prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin.
title_sort prevention of metastasis from mouse mammary carcinomas with liposomes carrying doxorubicin.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033931/
https://www.ncbi.nlm.nih.gov/pubmed/7577449
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AT loftust preventionofmetastasisfrommousemammarycarcinomaswithliposomescarryingdoxorubicin
AT workingp preventionofmetastasisfrommousemammarycarcinomaswithliposomescarryingdoxorubicin

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