Molecular genetic evidence for unifocal origin of advanced epithelial ovarian cancer and for minor clonal divergence.

Detection of loss of heterozygosity (LOH) and DNA flow cytometry (FCM) were used to trace the origin of bilateral ovarian cancer from 16 patients. From each tumour the DNA index (DI) and LOH patterns for chromosomes 1, 3, 6, 11, 17, 18, 22 and X were determined with 36 microsatellite markers. Formal...

Descripción completa

Detalles Bibliográficos
Autores principales: Abeln, E. C., Kuipers-Dijkshoorn, N. J., Berns, E. M., Henzen-Logmans, S. C., Fleuren, G. J., Cornelisse, C. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033953/
https://www.ncbi.nlm.nih.gov/pubmed/7577492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2033953/
https://www.ncbi.nlm.nih.gov/pubmed/7577492

Ejemplares similares