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Infrequent CDKN2 (MTS1/p16) gene alterations in human primary breast cancer.
Changes which lead to excessive cyclin production or to loss of cell cycle inhibition by proteins such as p16/MTS1 may release breast tumour cells from the constraints of cell division. In order to establish the frequency of MTS1/p16 gene alteration and its relation with genetic damage to the p53 an...
Autores principales: | Berns, E. M., Klijn, J. G., Smid, M., van Staveren, I. L., Gruis, N. A., Foekens, J. A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034024/ https://www.ncbi.nlm.nih.gov/pubmed/7547249 |
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