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Design of extended short hairpin RNAs for HIV-1 inhibition

RNA interference (RNAi) targeted towards viral mRNAs is widely used to block virus replication in mammalian cells. The specific antiviral RNAi response can be induced via transfection of synthetic small interfering RNAs (siRNAs) or via intracellular expression of short hairpin RNAs (shRNAs). For HIV...

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Detalles Bibliográficos
Autores principales:	Liu, Ying Poi, Haasnoot, Joost, Berkhout, Ben
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034457/ https://www.ncbi.nlm.nih.gov/pubmed/17715143 http://dx.doi.org/10.1093/nar/gkm596

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