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Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media

In this study the reliability and validity of generic and disease-specific questionnaires has been assessed focusing on responsiveness. This is part of a study on the effects of recurrent acute otitis media (rAOM) on functional health status (FHS) and health-related quality of life (HRQoL) in 383 ch...

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Autores principales: Brouwer, Carole N. M., Schilder, Anne G. M., van Stel, Henk F., Rovers, Maroeska M., Veenhoven, Reinier H., Grobbee, Diederick E., Sanders, Elisabeth A. M., Maillé, A. Rianne
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039822/
https://www.ncbi.nlm.nih.gov/pubmed/17668290
http://dx.doi.org/10.1007/s11136-007-9242-0
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author Brouwer, Carole N. M.
Schilder, Anne G. M.
van Stel, Henk F.
Rovers, Maroeska M.
Veenhoven, Reinier H.
Grobbee, Diederick E.
Sanders, Elisabeth A. M.
Maillé, A. Rianne
author_facet Brouwer, Carole N. M.
Schilder, Anne G. M.
van Stel, Henk F.
Rovers, Maroeska M.
Veenhoven, Reinier H.
Grobbee, Diederick E.
Sanders, Elisabeth A. M.
Maillé, A. Rianne
author_sort Brouwer, Carole N. M.
collection PubMed
description In this study the reliability and validity of generic and disease-specific questionnaires has been assessed focusing on responsiveness. This is part of a study on the effects of recurrent acute otitis media (rAOM) on functional health status (FHS) and health-related quality of life (HRQoL) in 383 children with rAOM participating in a randomized clinical trial. The following generic questionnaires were studied: 1. RAND general health rating index, 2. Functional Status Questionnaire (FSQ Generic and FSQ Specific), 3. TNO-AZL Infant Quality of Life (TAIQOL), and the following disease-specific questionnaires: 1. Otitis Media-6 (OM-6), 2. Numerical rating scales (NRS) for child and caregiver (NRS Child and NRS Caregiver), and 3. a new Family Functioning Questionnaire (FFQ). Reliability was good to excellent (Cronbach’s α range 0.80–0.90, intraclass correlation coefficient range 0.76–0.93). Moderate to strong correlations were found between the questionnaires as well as between questionnaires and relevant clinical indicators (r = 0.29–0.49), demonstrating construct validity. Discriminant validity for children with few versus frequent episodes of acute otitis media per year was good for most questionnaires (P < 0.004) but poor for the otitis media-related subscales of the TAIQOL (P = 0.10–0.97) and both NRS (P = 0.22 and 0.48). Except for the TAIQOL subscales, change scores were significant (P < 0.003) for generic and disease-specific questionnaires. Effect sizes were somewhat higher for disease-specific compared to generic questionnaires (0.55–0.95 versus 0.32–0.60) except for the TAIQOL subscales, which showed very poor sensitivity to change. Anchor-based methods resulted in a somewhat larger range of estimates of MCID than distribution-based methods. Combining distribution-based and anchor-based methods resulted in similar ranges for the minimally clinical important differences for generic and disease-specific questionnaires: 2–15 points on a 0–100 scale. Apart from the generic TAIQOL subscales, both generic and disease-specific questionnaires used in this study showed good psychometric qualities and responsiveness for use in clinical studies on children with rAOM.
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spelling pubmed-20398222007-10-29 Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media Brouwer, Carole N. M. Schilder, Anne G. M. van Stel, Henk F. Rovers, Maroeska M. Veenhoven, Reinier H. Grobbee, Diederick E. Sanders, Elisabeth A. M. Maillé, A. Rianne Qual Life Res Article In this study the reliability and validity of generic and disease-specific questionnaires has been assessed focusing on responsiveness. This is part of a study on the effects of recurrent acute otitis media (rAOM) on functional health status (FHS) and health-related quality of life (HRQoL) in 383 children with rAOM participating in a randomized clinical trial. The following generic questionnaires were studied: 1. RAND general health rating index, 2. Functional Status Questionnaire (FSQ Generic and FSQ Specific), 3. TNO-AZL Infant Quality of Life (TAIQOL), and the following disease-specific questionnaires: 1. Otitis Media-6 (OM-6), 2. Numerical rating scales (NRS) for child and caregiver (NRS Child and NRS Caregiver), and 3. a new Family Functioning Questionnaire (FFQ). Reliability was good to excellent (Cronbach’s α range 0.80–0.90, intraclass correlation coefficient range 0.76–0.93). Moderate to strong correlations were found between the questionnaires as well as between questionnaires and relevant clinical indicators (r = 0.29–0.49), demonstrating construct validity. Discriminant validity for children with few versus frequent episodes of acute otitis media per year was good for most questionnaires (P < 0.004) but poor for the otitis media-related subscales of the TAIQOL (P = 0.10–0.97) and both NRS (P = 0.22 and 0.48). Except for the TAIQOL subscales, change scores were significant (P < 0.003) for generic and disease-specific questionnaires. Effect sizes were somewhat higher for disease-specific compared to generic questionnaires (0.55–0.95 versus 0.32–0.60) except for the TAIQOL subscales, which showed very poor sensitivity to change. Anchor-based methods resulted in a somewhat larger range of estimates of MCID than distribution-based methods. Combining distribution-based and anchor-based methods resulted in similar ranges for the minimally clinical important differences for generic and disease-specific questionnaires: 2–15 points on a 0–100 scale. Apart from the generic TAIQOL subscales, both generic and disease-specific questionnaires used in this study showed good psychometric qualities and responsiveness for use in clinical studies on children with rAOM. Springer Netherlands 2007-08-01 2007-10 /pmc/articles/PMC2039822/ /pubmed/17668290 http://dx.doi.org/10.1007/s11136-007-9242-0 Text en © Springer Science+Business Media B.V. 2007
spellingShingle Article
Brouwer, Carole N. M.
Schilder, Anne G. M.
van Stel, Henk F.
Rovers, Maroeska M.
Veenhoven, Reinier H.
Grobbee, Diederick E.
Sanders, Elisabeth A. M.
Maillé, A. Rianne
Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media
title Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media
title_full Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media
title_fullStr Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media
title_full_unstemmed Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media
title_short Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media
title_sort reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis media
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039822/
https://www.ncbi.nlm.nih.gov/pubmed/17668290
http://dx.doi.org/10.1007/s11136-007-9242-0
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