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Preoperative Chemoradiotherapy with Capecitabine and Oxaliplatin in Locally Advanced Rectal Cancer. A Phase I–II Multicenter Study of the Dutch Colorectal Cancer Group

BACKGROUND: We studied the maximum tolerated dose (MTD) and efficacy of oxaliplatin added to capecitabine and radiotherapy (Capox-RT) as neoadjuvant therapy for rectal cancer. METHODS: T3-4 rectal cancer patients received escalating doses of oxaliplatin (day 1 and 29) with a fixed dose of capecitabi...

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Detalles Bibliográficos
Autores principales:	Hospers, Geke A., Punt, Cornelis J. A., Tesselaar, Margot E., Cats, Annemieke, Havenga, Klaas, Leer, Jan W. H., Marijnen, Corrie A., Jansen, Edwin P., Van Krieken, Han H. J. M., Wiggers, Theo, Van de Velde, Cornelis J. H., Mulder, Nanno H.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2007
Materias:	Gastrointestinal Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039827/ https://www.ncbi.nlm.nih.gov/pubmed/17653805 http://dx.doi.org/10.1245/s10434-007-9396-6

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