Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics

BACKGROUND: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of peptides to MS/MS spectra by SEQUEST searching algorithm are defined by several scores including Xcorr, ΔCn, Sp, Rsp, matched...

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Detalles Bibliográficos
Autores principales: Jiang, Xinning, Jiang, Xiaogang, Han, Guanghui, Ye, Mingliang, Zou, Hanfa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040164/
https://www.ncbi.nlm.nih.gov/pubmed/17761002
http://dx.doi.org/10.1186/1471-2105-8-323

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