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GH responsiveness in a large multinational cohort of SGA children with short stature (NESTEGG) is related to the exon 3 GHR polymorphism

OBJECTIVE: The polymorphic deletion of exon 3 of the GH receptor (d3-GHR) has recently been linked to the magnitude of growth response to recombinant human GH (rhGH) therapy in short children with or without GH deficiency. We investigated this association in a large multinational cohort from the Net...

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Detalles Bibliográficos
Autores principales: Tauber, M, Ester, W, Auriol, F, Molinas, C, Fauvel, J, Caliebe, J, Nugent, T, Fryklund, L, Ranke, M B, Savage, M O, Clark, A J L, Johnston, L B, Hokken-Koelega, A C S
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040241/
https://www.ncbi.nlm.nih.gov/pubmed/17555507
http://dx.doi.org/10.1111/j.1365-2265.2007.02911.x