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The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843

Lactic acid was first found and described in sour milk by Karl Wilhelm Scheele (1742–1786) in 1780. The German physician–chemist Johann Joseph Scherer (1841–1869) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 and 1851. In this article we honour the f...

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Detalles Bibliográficos
Autores principales: Kompanje, E. J. O., Jansen, T. C., van der Hoven, B., Bakker, J.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040486/
https://www.ncbi.nlm.nih.gov/pubmed/17661014
http://dx.doi.org/10.1007/s00134-007-0788-7
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author Kompanje, E. J. O.
Jansen, T. C.
van der Hoven, B.
Bakker, J.
author_facet Kompanje, E. J. O.
Jansen, T. C.
van der Hoven, B.
Bakker, J.
author_sort Kompanje, E. J. O.
collection PubMed
description Lactic acid was first found and described in sour milk by Karl Wilhelm Scheele (1742–1786) in 1780. The German physician–chemist Johann Joseph Scherer (1841–1869) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 and 1851. In this article we honour the forgotten observations by Scherer and describe the influence of Scherer's finding on further research on lactic acid at the end of the 19th century. We conclude that Scherer's 1843 case reports should be cited as the first description of lactic acid in human blood after death and also as the first demonstration of lactic acid as a pathological finding in septic and haemorrhagic shock. Carl Folwarczny was, in 1858, the first to demonstrate lactic acid in blood in a living patient.
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spelling pubmed-20404862007-10-29 The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843 Kompanje, E. J. O. Jansen, T. C. van der Hoven, B. Bakker, J. Intensive Care Med Original Lactic acid was first found and described in sour milk by Karl Wilhelm Scheele (1742–1786) in 1780. The German physician–chemist Johann Joseph Scherer (1841–1869) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 and 1851. In this article we honour the forgotten observations by Scherer and describe the influence of Scherer's finding on further research on lactic acid at the end of the 19th century. We conclude that Scherer's 1843 case reports should be cited as the first description of lactic acid in human blood after death and also as the first demonstration of lactic acid as a pathological finding in septic and haemorrhagic shock. Carl Folwarczny was, in 1858, the first to demonstrate lactic acid in blood in a living patient. Springer-Verlag 2007-07-28 2007-11 /pmc/articles/PMC2040486/ /pubmed/17661014 http://dx.doi.org/10.1007/s00134-007-0788-7 Text en © Springer-Verlag 2007
spellingShingle Original
Kompanje, E. J. O.
Jansen, T. C.
van der Hoven, B.
Bakker, J.
The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843
title The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843
title_full The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843
title_fullStr The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843
title_full_unstemmed The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843
title_short The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843
title_sort first demonstration of lactic acid in human blood in shock by johann joseph scherer (1814–1869) in january 1843
topic Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040486/
https://www.ncbi.nlm.nih.gov/pubmed/17661014
http://dx.doi.org/10.1007/s00134-007-0788-7
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