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The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843
Lactic acid was first found and described in sour milk by Karl Wilhelm Scheele (1742–1786) in 1780. The German physician–chemist Johann Joseph Scherer (1841–1869) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 and 1851. In this article we honour the f...
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Formato: | Texto |
Lenguaje: | English |
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Springer-Verlag
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040486/ https://www.ncbi.nlm.nih.gov/pubmed/17661014 http://dx.doi.org/10.1007/s00134-007-0788-7 |
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author | Kompanje, E. J. O. Jansen, T. C. van der Hoven, B. Bakker, J. |
author_facet | Kompanje, E. J. O. Jansen, T. C. van der Hoven, B. Bakker, J. |
author_sort | Kompanje, E. J. O. |
collection | PubMed |
description | Lactic acid was first found and described in sour milk by Karl Wilhelm Scheele (1742–1786) in 1780. The German physician–chemist Johann Joseph Scherer (1841–1869) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 and 1851. In this article we honour the forgotten observations by Scherer and describe the influence of Scherer's finding on further research on lactic acid at the end of the 19th century. We conclude that Scherer's 1843 case reports should be cited as the first description of lactic acid in human blood after death and also as the first demonstration of lactic acid as a pathological finding in septic and haemorrhagic shock. Carl Folwarczny was, in 1858, the first to demonstrate lactic acid in blood in a living patient. |
format | Text |
id | pubmed-2040486 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-20404862007-10-29 The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843 Kompanje, E. J. O. Jansen, T. C. van der Hoven, B. Bakker, J. Intensive Care Med Original Lactic acid was first found and described in sour milk by Karl Wilhelm Scheele (1742–1786) in 1780. The German physician–chemist Johann Joseph Scherer (1841–1869) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 and 1851. In this article we honour the forgotten observations by Scherer and describe the influence of Scherer's finding on further research on lactic acid at the end of the 19th century. We conclude that Scherer's 1843 case reports should be cited as the first description of lactic acid in human blood after death and also as the first demonstration of lactic acid as a pathological finding in septic and haemorrhagic shock. Carl Folwarczny was, in 1858, the first to demonstrate lactic acid in blood in a living patient. Springer-Verlag 2007-07-28 2007-11 /pmc/articles/PMC2040486/ /pubmed/17661014 http://dx.doi.org/10.1007/s00134-007-0788-7 Text en © Springer-Verlag 2007 |
spellingShingle | Original Kompanje, E. J. O. Jansen, T. C. van der Hoven, B. Bakker, J. The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843 |
title | The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843 |
title_full | The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843 |
title_fullStr | The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843 |
title_full_unstemmed | The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843 |
title_short | The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843 |
title_sort | first demonstration of lactic acid in human blood in shock by johann joseph scherer (1814–1869) in january 1843 |
topic | Original |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040486/ https://www.ncbi.nlm.nih.gov/pubmed/17661014 http://dx.doi.org/10.1007/s00134-007-0788-7 |
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