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Target Cell APOBEC3C Can Induce Limited G-to-A Mutation in HIV-1

The evolutionary success of primate lentiviruses reflects their high capacity to mutate and adapt to new host species, immune responses within individual hosts, and, in recent years, antiviral drugs. APOBEC3G (A3G) and APOBEC3F (A3F) are host cell DNA-editing enzymes that induce extensive HIV-1 muta...

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Detalles Bibliográficos
Autores principales: Bourara, Khaoula, Liegler, Teri J, Grant, Robert M
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042017/
https://www.ncbi.nlm.nih.gov/pubmed/17967058
http://dx.doi.org/10.1371/journal.ppat.0030153

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