Small-Molecule Inhibition of HIV pre-mRNA Splicing as a Novel Antiretroviral Therapy to Overcome Drug Resistance

The development of multidrug-resistant viruses compromises antiretroviral therapy efficacy and limits therapeutic options. Therefore, it is an ongoing task to identify new targets for antiretroviral therapy and to develop new drugs. Here, we show that an indole derivative (IDC16) that interferes wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Bakkour, Nadia, Lin, Yea-Lih, Maire, Sophie, Ayadi, Lilia, Mahuteau-Betzer, Florence, Nguyen, Chi Hung, Mettling, Clément, Portales, Pierre, Grierson, David, Chabot, Benoit, Jeanteur, Philippe, Branlant, Christiane, Corbeau, Pierre, Tazi, Jamal
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042022/
https://www.ncbi.nlm.nih.gov/pubmed/17967062
http://dx.doi.org/10.1371/journal.ppat.0030159

Ejemplares similares

Ejemplares similares