Variants in the FFAR1 Gene Are Associated with Beta Cell Function

BACKGROUND: The FFAR1 receptor is expressed mainly in pancreatic beta cells and is activated by medium to long chain free fatty acids (FFAs), as well as by thiazolidinediones, resulting in elevated Ca(2+) concentrations and promotion of insulin secretion. These properties suggest that FFAR1 could be...

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Detalles Bibliográficos
Autores principales: Kalis, Martins, Levéen, Per, Lyssenko, Valeriya, Almgren, Peter, Groop, Leif, Cilio, Corrado M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042513/
https://www.ncbi.nlm.nih.gov/pubmed/17987108
http://dx.doi.org/10.1371/journal.pone.0001090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042513/
https://www.ncbi.nlm.nih.gov/pubmed/17987108
http://dx.doi.org/10.1371/journal.pone.0001090

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