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Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells

This study aimed to demonstrate that microspheres, used as delivery vehicle of DNA-Hsp65/TDM [plasmid DNA encoding heat shock protein 65 (Hsp65) coencapsulated with trehalose dimycolate (TDM) into PLGA microspheres], are widely spread among several organs after intramuscular administration in BALB/c...

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Detalles Bibliográficos
Autores principales:	Trombone, Ana Paula F, Silva, Celio L, Almeida, Luciana P, Rosada, Rogerio S, Lima, Karla M, Oliver, Constance, Jamur, Maria C, Coelho-Castelo, Arlete AM
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042973/ https://www.ncbi.nlm.nih.gov/pubmed/17880727 http://dx.doi.org/10.1186/1479-0556-5-9

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