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Distinct evolutionary mechanisms for genomic imbalances in high-risk and low-risk neuroblastomas
BACKGROUND: Neuroblastoma (NB) is the most common extracranial solid tumour of childhood. Several genomic imbalances correlate to prognosis in NB, with structural rearrangements, including gene amplification, in a near-diploid setting typically signifying high-risk tumours and numerical changes in a...
Autores principales: | Gisselsson, David, Lundberg, Gisela, Øra, Ingrid, Höglund, Mattias |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042979/ https://www.ncbi.nlm.nih.gov/pubmed/17897457 http://dx.doi.org/10.1186/1477-3163-6-15 |
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