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New active site oriented glyoxyl-agarose derivatives of Escherichia coli penicillin G acylase

BACKGROUND: Immobilized Penicillin G Acylase (PGA) derivatives are biocatalysts that are industrially used for the hydrolysis of Penicillin G by fermentation and for the kinetically controlled synthesis of semi-synthetic β-lactam antibiotics. One of the most used supports for immobilization is glyox...

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Detalles Bibliográficos
Autores principales: Cecchini, Davide A, Serra, Immacolata, Ubiali, Daniela, Terreni, Marco, Albertini, Alessandra M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045090/
https://www.ncbi.nlm.nih.gov/pubmed/17845725
http://dx.doi.org/10.1186/1472-6750-7-54