Cargando…

Effects of mu- and kappa-2 opioid receptor agonists on pain and rearing behaviors

BACKGROUND: Management of pain involves a balance between inhibition of pain and minimization of side effects; therefore, in developing new analgesic compounds, one must consider the effects of treatment on both pain processing and behavior. The purpose of this study was to evaluate the effects of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neubert, John K, Rossi, Heather L, Pogar, Jonathan, Jenkins, Alan C, Caudle, Robert M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045099/ https://www.ncbi.nlm.nih.gov/pubmed/17883847 http://dx.doi.org/10.1186/1744-9081-3-49

Ejemplares similares

Orvinols with Mixed Kappa/Mu Opioid Receptor Agonist Activity
por: Greedy, Benjamin M., et al.
Publicado: (2013)

Differential Stability of the Crystallographic Interfaces of Mu- and Kappa-Opioid Receptors
por: Johnston, Jennifer M., et al.
Publicado: (2014)

Role of kappa‐opioid and mu‐opioid receptors in pruritus: Peripheral and central itch circuits
por: Kim, Brian S., et al.
Publicado: (2022)

Genetic Analysis of Mu and Kappa Opioid Receptor and COMT Enzyme in Cancer Pain Tunisian Patients Under Opioid Treatment
por: CHATTI, Imen, et al.
Publicado: (2017)

Therapeutic Potential of Kappa Opioid Agonists
por: Beck, Tyler C., et al.
Publicado: (2019)

Kappa but not delta or mu opioid receptors form homodimers at low membrane densities
por: Cechova, Kristina, et al.
Publicado: (2021)

Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonists
por: Murányi, Marianna, et al.
Publicado: (2013)

Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D(2) Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor
por: Vasudevan, Lakshmi, et al.
Publicado: (2019)

Development of a Peptide-Derived Orally-Active Kappa-Opioid Receptor Agonist Targeting Peripheral Pain
por: Hughes, Jr, Francis M., et al.
Publicado: (2013)

Sex Differences in Kappa Opioid Receptor Agonist Mediated Attenuation of Chemotherapy-Induced Neuropathic Pain in Mice
por: Paton, Kelly F., et al.
Publicado: (2022)

Antipruritic Effect of Nalbuphine, a Kappa Opioid Receptor Agonist, in Mice: A Pan Antipruritic
por: Inan, Saadet, et al.
Publicado: (2021)

Novel Kappa-Opioid Receptor Agonist for the Treatment of Cholestatic Pruritus: Systematic Review
por: Bailey, Adrian Joseph Michel, et al.
Publicado: (2022)

Placement of Hydroxy Moiety on Pendant of Peptidomimetic Scaffold Modulates Mu and Kappa Opioid Receptor Efficacy
por: Harland, Aubrie A., et al.
Publicado: (2017)

Discovery of the First Small-Molecule Opioid Pan Antagonist with Nanomolar Affinity at Mu, Delta, Kappa, and Nociceptin Opioid Receptors
por: Zaveri, Nurulain T., et al.
Publicado: (2015)

Dynamic lateral organization of opioid receptors (kappa, mu(wt) and mu(N40D)) in the plasma membrane at the nanoscale level
por: Rogacki, Maciej K., et al.
Publicado: (2018)

In vitro and in vivo Pharmacological Activities of 14-O-Phenylpropyloxymorphone, a Potent Mixed Mu/Delta/Kappa-Opioid Receptor Agonist With Reduced Constipation in Mice
por: Lattanzi, Roberta, et al.
Publicado: (2018)

Recent Molecular Insights into Agonist-specific Binding to the Mu-Opioid Receptor
por: Zádor, Ferenc, et al.
Publicado: (2022)

nor-BNI Antagonism of Kappa Opioid Agonist-Induced Reinstatement of Ethanol-Seeking Behavior
por: Harshberger, Erin, et al.
Publicado: (2016)

Role of mu opioid receptor (MOR) agonist efficacy as a determinant of opioid antinociception in a novel assay of pain-depressed behavior in female and male mice
por: Negus, S. Stevens, et al.
Publicado: (2023)

Does the kappa opioid receptor system contribute to pain aversion?
por: Cahill, Catherine M., et al.
Publicado: (2014)

Characterization of mouse orofacial pain and the effects of lesioning TRPV1-expressing neurons on operant behavior
por: Neubert, John K, et al.
Publicado: (2008)

Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation
por: Shokirova, Hurramhon, et al.
Publicado: (2021)

Characterization of Pyrrolidinyl-hexahydro-pyranopiperazines as a Novel Kappa Opioid Receptor Agonist Scaffold
por: Reed, Brian, et al.
Publicado: (2022)

Neurons derived from human-induced pluripotent stem cells express mu and kappa opioid receptors
por: Ju, Zhi-Hai, et al.
Publicado: (2020)

Behavioral Pharmacology of Novel Kappa Opioid Receptor Antagonists in Rats
por: Page, Sarah, et al.
Publicado: (2019)

Signaling underlying kappa opioid receptor-mediated behaviors in rodents
por: Liu-Chen, Lee-Yuan, et al.
Publicado: (2022)

Mu opioid receptor: from pain to glucose metabolism
por: Tudurí, Eva, et al.
Publicado: (2016)

A Structure-Activity Relationship Comparison of Imidazodiazepines Binding at Kappa, Mu, and Delta Opioid Receptors and the GABA(A) Receptor
por: Li, Guanguan, et al.
Publicado: (2020)

The Effects of a Co-Application of Menthol and Capsaicin on Nociceptive Behaviors of the Rat on the Operant Orofacial Pain Assessment Device
por: Anderson, Ethan M., et al.
Publicado: (2014)

Probing ligand recognition of the opioid pan antagonist AT-076 at nociceptin, kappa, mu, and delta opioid receptors through structure-activity relationships
por: Journigan, V. Blair, et al.
Publicado: (2017)

Antinociceptive and Antipruritic Effects of HSK21542, a Peripherally-Restricted Kappa Opioid Receptor Agonist, in Animal Models of Pain and Itch
por: Wang, Xin, et al.
Publicado: (2021)

Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors
por: Shen, Qianwei, et al.
Publicado: (2017)

Diuretic Activity of a Novel Peripherally-Restricted Orally-Active Kappa Opioid Receptor Agonist
por: Beck, Tyler C., et al.
Publicado: (2019)

Varying Expression of Mu and Kappa Opioid Receptors in Cockatiels (Nymphicus hollandicus) and Domestic Pigeons (Columba livia domestica)
por: Fousse, Samantha L., et al.
Publicado: (2020)

Pharmacological profiles of opioid ligands at Kappa opioid receptors
por: Gharagozlou, Parham, et al.
Publicado: (2006)

In vivo antinociception of potent mu opioid agonist tetrapeptide analogues and comparison with a compact opioid agonist - neurokinin 1 receptor antagonist chimera
por: Guillemyn, Karel, et al.
Publicado: (2012)

Evaluation of the abuse potential of difelikefalin, a selective kappa‐opioid receptor agonist, in recreational polydrug users
por: Shram, Megan J., et al.
Publicado: (2021)

Targeting Peripheral Kappa Opioid Receptors for the Treatment of Chronic Pain: Review Article
por: Beck, Tyler C, et al.
Publicado: (2019)

A2 ACUTE COLITIS CAUSES CHANGES TO THE EFFICACY OF CANNABINOID-1 AND MU-OPIOID RECEPTOR AGONISTS ON INHIBITING ABDOMINAL PAIN
por: Tsang, Q K, et al.
Publicado: (2023)

Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists
por: Kaserer, Teresa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m281f1k1gm282lhqsedf41isf3