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An investigation of the effects of lipid-lowering medications: genome-wide linkage analysis of lipids in the HyperGEN study

BACKGROUND: Use of anti-hyperlipidemic medications compromises genetic analysis because of altered lipid profiles. We propose an empirical method to adjust lipid levels for medication effects so that the adjusted lipid values substitute the unmedicated lipid values in the genetic analysis. RESULTS:...

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Detalles Bibliográficos
Autores principales: Wu, Jun, Province, Michael A, Coon, Hilary, Hunt, Steven C, Eckfeldt, John H, Arnett, Donna K, Heiss, Gerardo, Lewis, Cora E, Ellison, R Curtis, Rao, Dabeeru C, Rice, Treva, Kraja, Aldi T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045675/
https://www.ncbi.nlm.nih.gov/pubmed/17845730
http://dx.doi.org/10.1186/1471-2156-8-60