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Mucinous adenocarcinoma presenting as an isolated sternal metastasis

BACKGROUND: As a result of improvements in diagnostic accuracy, the primary source of the tumour is identified in more than 99% of cases presenting with a malignancy. Whilst the axial skeleton is a common site of metastases, the sternum is rarely affected, especially by isolated metastases. CASE PRE...

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Autores principales: Ball, Elizabeth, Morris-Stiff, Gareth, Coxon, Mari, Lewis, Michael H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048510/
https://www.ncbi.nlm.nih.gov/pubmed/17892541
http://dx.doi.org/10.1186/1477-7819-5-105
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author Ball, Elizabeth
Morris-Stiff, Gareth
Coxon, Mari
Lewis, Michael H
author_facet Ball, Elizabeth
Morris-Stiff, Gareth
Coxon, Mari
Lewis, Michael H
author_sort Ball, Elizabeth
collection PubMed
description BACKGROUND: As a result of improvements in diagnostic accuracy, the primary source of the tumour is identified in more than 99% of cases presenting with a malignancy. Whilst the axial skeleton is a common site of metastases, the sternum is rarely affected, especially by isolated metastases. CASE PRESENTATION: We report a case of a 68 year old male who was referred to the surgical outpatient clinic with a six month history of sternal pain. The patient was known to have essential thrombocythaemia, which had recently transformed into acute myeloid leukaemia but a sternal biospy showed mucinous adenocarcinoma. He had not localising symptoms and full evaluation failed to localise the primary tumour. CONCLUSION: Solitary sternal metastases are rare and when found an underlying neoplasm is usually identified allowing targeted treatment. If however, there is no symptomatic tumour, the metastasis should simply be treated symptomatically.
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spelling pubmed-20485102007-11-01 Mucinous adenocarcinoma presenting as an isolated sternal metastasis Ball, Elizabeth Morris-Stiff, Gareth Coxon, Mari Lewis, Michael H World J Surg Oncol Case Report BACKGROUND: As a result of improvements in diagnostic accuracy, the primary source of the tumour is identified in more than 99% of cases presenting with a malignancy. Whilst the axial skeleton is a common site of metastases, the sternum is rarely affected, especially by isolated metastases. CASE PRESENTATION: We report a case of a 68 year old male who was referred to the surgical outpatient clinic with a six month history of sternal pain. The patient was known to have essential thrombocythaemia, which had recently transformed into acute myeloid leukaemia but a sternal biospy showed mucinous adenocarcinoma. He had not localising symptoms and full evaluation failed to localise the primary tumour. CONCLUSION: Solitary sternal metastases are rare and when found an underlying neoplasm is usually identified allowing targeted treatment. If however, there is no symptomatic tumour, the metastasis should simply be treated symptomatically. BioMed Central 2007-09-24 /pmc/articles/PMC2048510/ /pubmed/17892541 http://dx.doi.org/10.1186/1477-7819-5-105 Text en Copyright © 2007 Ball et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ball, Elizabeth
Morris-Stiff, Gareth
Coxon, Mari
Lewis, Michael H
Mucinous adenocarcinoma presenting as an isolated sternal metastasis
title Mucinous adenocarcinoma presenting as an isolated sternal metastasis
title_full Mucinous adenocarcinoma presenting as an isolated sternal metastasis
title_fullStr Mucinous adenocarcinoma presenting as an isolated sternal metastasis
title_full_unstemmed Mucinous adenocarcinoma presenting as an isolated sternal metastasis
title_short Mucinous adenocarcinoma presenting as an isolated sternal metastasis
title_sort mucinous adenocarcinoma presenting as an isolated sternal metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048510/
https://www.ncbi.nlm.nih.gov/pubmed/17892541
http://dx.doi.org/10.1186/1477-7819-5-105
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AT morrisstiffgareth mucinousadenocarcinomapresentingasanisolatedsternalmetastasis
AT coxonmari mucinousadenocarcinomapresentingasanisolatedsternalmetastasis
AT lewismichaelh mucinousadenocarcinomapresentingasanisolatedsternalmetastasis