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“Negative Vaccination” by Specific CD4(+) T Cell Tolerisation Enhances Virus-Specific Protective Antibody Responses

BACKGROUND: Cooperation of CD4(+) T helper cells with specific B cells is crucial for protective vaccination against pathogens by inducing long-lived neutralizing antibody responses. During infection with persistence-prone viruses, prolonged virus replication correlates with low neutralizing antibod...

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Detalles Bibliográficos
Autores principales:	Lang, Karl S., Hegazy, Ahmed N., Lang, Philipp A., Eschli, Bruno, Löhning, Max, Hengartner, Hans, Zinkernagel, Rolf M., Recher, Mike
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048666/ https://www.ncbi.nlm.nih.gov/pubmed/18000535 http://dx.doi.org/10.1371/journal.pone.0001162

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