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Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1)
How proteins participate in tumorigenesis can be obscured by their multifunctional nature. For example, depending on the cellular context, the cdk inhibitors can affect cell proliferation, cell motility, apoptosis, receptor tyrosine kinase signaling, and transcription. Thus, to determine how a prote...
Autores principales: | Liu, Yuhui, Yeh, Nancy, Zhu, Xin-Hua, Leversha, Margaret, Cordon-Cardo, Carlos, Ghossein, Ronald, Singh, Bhuvanesh, Holland, Eric, Koff, Andrew |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048756/ https://www.ncbi.nlm.nih.gov/pubmed/17948060 http://dx.doi.org/10.1038/sj.emboj.7601886 |
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