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Common Activation of Canonical Wnt Signaling in Pancreatic Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDA) is an extremely aggressive malignancy, which carries a dismal prognosis. Activating mutations of the Kras gene are common to the vast majority of human PDA. In addition, recent studies have demonstrated that embryonic signaling pathway such as Hedgehog and Notc...
Autores principales: | Pasca di Magliano, Marina, Biankin, Andrew V., Heiser, Patrick W., Cano, David A., Gutierrez, Pedro J. A., Deramaudt, Therese, Segara, Davendra, Dawson, Amanda C., Kench, James G., Henshall, Susan M., Sutherland, Robert L., Dlugosz, Andrzej, Rustgi, Anil K., Hebrok, Matthias |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048934/ https://www.ncbi.nlm.nih.gov/pubmed/17982507 http://dx.doi.org/10.1371/journal.pone.0001155 |
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