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Common Activation of Canonical Wnt Signaling in Pancreatic Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) is an extremely aggressive malignancy, which carries a dismal prognosis. Activating mutations of the Kras gene are common to the vast majority of human PDA. In addition, recent studies have demonstrated that embryonic signaling pathway such as Hedgehog and Notc...

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Detalles Bibliográficos
Autores principales: Pasca di Magliano, Marina, Biankin, Andrew V., Heiser, Patrick W., Cano, David A., Gutierrez, Pedro J. A., Deramaudt, Therese, Segara, Davendra, Dawson, Amanda C., Kench, James G., Henshall, Susan M., Sutherland, Robert L., Dlugosz, Andrzej, Rustgi, Anil K., Hebrok, Matthias
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048934/
https://www.ncbi.nlm.nih.gov/pubmed/17982507
http://dx.doi.org/10.1371/journal.pone.0001155

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