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Haematopoietic development and immunological function in the absence of cathepsin D

BACKGROUND: Cathepsin D is a well-characterized aspartic protease expressed ubiquitously in lysosomes. Cathepsin D deficiency is associated with a spectrum of pathologies leading ultimately to death. Cathepsin D is expressed at high levels in many cells of the immune system, but its role in immune f...

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Detalles Bibliográficos
Autores principales:	Tulone, Calogero, Uchiyama, Yasuo, Novelli, Marco, Grosvenor, Nicholas, Saftig, Paul, Chain, Benjamin M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central\|1 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048983/ https://www.ncbi.nlm.nih.gov/pubmed/17897442 http://dx.doi.org/10.1186/1471-2172-8-22

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