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Mutations in the TP53 gene and protein expression of p53, MDM 2 and p21/WAF-1 in primary cervical carcinomas with no or low human papillomavirus load.
Several studies have focused on the role of p53 inactivation in cervical cancer, either by inactivating mutations in the TP53 gene or by degradation of the p53 protein by human papillomavirus (HPV). In this study, primary cervical carcinomas from 365 patients were analysed for presence of HPV using...
Autores principales: | Helland, A., Karlsen, F., Due, E. U., Holm, R., Kristensen, G., Børresen-Dale, A. l. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group|1
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2062929/ https://www.ncbi.nlm.nih.gov/pubmed/9662253 |
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