Cargando…
A phase I study of the vitamin D analogue EB 1089 in patients with advanced breast and colorectal cancer.
Preclinical studies have shown that the vitamin D analogue EB 1089 has significantly less calcaemic activity than its parent compound 1,25-dihydroxyvitamin D (1,25(OH)2D3) and significant anti-tumour activity. This phase I trial was designed to evaluate the calcaemic effect of the drug in patients w...
Autores principales: | Gulliford, T., English, J., Colston, K. W., Menday, P., Moller, S., Coombes, R. C. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group|1
1998
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2062933/ https://www.ncbi.nlm.nih.gov/pubmed/9662243 |
Ejemplares similares
-
A phase II trial of the vitamin D analogue Seocalcitol (EB1089) in patients with inoperable pancreatic cancer
por: Evans, T R J, et al.
Publicado: (2002) -
The vitamin D receptor agonist EB1089 can exert its antiviral activity independently of the vitamin D receptor
por: Jaratsittisin, Janejira, et al.
Publicado: (2023) -
Anti-oestrogen resistant human breast cancer cell lines are more sensitive towards treatment with the vitamin D analogue EB1089 than parent MCF-7 cells
por: Larsen, S S, et al.
Publicado: (2001) -
SAT-353 The Synthetic Vitamin D Analog EB1089 Restricts Adrenocortical Tumor Proliferation in NCI-H295 Xenograft Model
por: Bueno, Ana, et al.
Publicado: (2019) -
EB1089 promotes the expression of vitamin D receptor in the intestinal epithelial cell line HT-29 and reduces lipopolysaccharide-induced inflammatory response
por: Lu, Dong, et al.
Publicado: (2022)