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Genetic analysis of lung tumours of non-smoking subjects: p53 gene mutations are constantly associated with loss of heterozygosity at the FHIT locus.
Lung cancer is strictly associated with tobacco smoking. Tumours developed in non-smoking subjects account for less than 10% of all lung cancers and show peculiar histopathological features, being prevalently adenocarcinomas. A number of genetic data suggest that their biological behaviour may be di...
Autores principales: | Marchetti, A., Pellegrini, S., Sozzi, G., Bertacca, G., Gaeta, P., Buttitta, F., Carnicelli, V., Griseri, P., Chella, A., Angeletti, C. A., Pierotti, M., Bevilacqua, G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group|1
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2062949/ https://www.ncbi.nlm.nih.gov/pubmed/9662254 |
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