Reversal of vinblastine transport by chlorpromazine in membrane vesicles from multidrug-resistant human CCRF-CEM leukaemia cells.

The mechanism of action of 2-chlorpromazine (2-chloro-10-(3-dimethylaminopropyl)-phenothiazine) as a reversal agent for P-glycoprotein-mediated multidrug resistance was investigated using inside out-orientated membrane vesicles prepared from vinblastine-resistant human CCRF-CEM leukaemia cells (VBL1...

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Detalles Bibliográficos
Autores principales: Syed, S. K., Christopherson, R. I., Roufogalis, B. D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063016/
https://www.ncbi.nlm.nih.gov/pubmed/9703277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063016/
https://www.ncbi.nlm.nih.gov/pubmed/9703277

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