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Biochemical basis of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation: a study in patients with (pre)malignant lesions of the oesophagus.
Administration of 5-aminolaevulinic acid (ALA) leads to porphyrin accumulation in malignant and premalignant tissues, and ALA is used as a prodrug in photodynamic therapy (PDT). To understand the mechanism of porphyrin accumulation after the administration of ALA and to investigate whether ALA-induc...
Autores principales: | Hinnen, P., de Rooij, F. W., van Velthuysen, M. L., Edixhoven, A., van Hillegersberg, R., Tilanus, H. W., Wilson, J. H., Siersema, P. D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group|1
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063052/ https://www.ncbi.nlm.nih.gov/pubmed/9744510 |
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