Evidence that an HLA-DQA1-DQB1 haplotype influences susceptibility to childhood common acute lymphoblastic leukaemia in boys provides further support for an infection-related aetiology.

Comparison of DQA1 and DQB1 alleles in 60 children with common acute lymphoblastic leukaemia (c-ALL) and 78 newborn infant control subjects revealed that male but not female patients had a higher frequency of DQA1*0101/*0104 and DQB1*0501 than appropriate control subjects. The results suggest a male...

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Detalles Bibliográficos
Autores principales: Taylor, G. M., Dearden, S., Payne, N., Ayres, M., Gokhale, D. A., Birch, J. M., Blair, V., Stevens, R. F., Will, A. M., Eden, O. B.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063058/
https://www.ncbi.nlm.nih.gov/pubmed/9744491

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