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Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumours.
Desmoids are locally aggressive, non-metastasizing soft-tissue tumours, whose aetiology is still unclear. In patients affected with familial adenomatous polyposis (FAP), the incidence of desmoids is much higher than in the general population. The APC gene, which is responsible for FAP, is involved i...
Autores principales: | Giarola, M., Wells, D., Mondini, P., Pilotti, S., Sala, P., Azzarelli, A., Bertario, L., Pierotti, M. A., Delhanty, J. D., Radice, P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group|1
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063069/ https://www.ncbi.nlm.nih.gov/pubmed/9744495 |
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