Cargando…

Mechanism of muscle protein degradation induced by a cancer cachectic factor.

A proteolysis-inducing factor (PIF) isolated from a cachexia-inducing murine tumour (MAC16) produced a decrease in body weight (1.6 g, P < or = 0.01 compared with control subjects) within 24 h after i.v. administration to non-tumour-bearing mice. Weight loss was associated with significant decrea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lorite, M. J., Thompson, M. G., Drake, J. L., Carling, G., Tisdale, M. J.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group\|1 1998
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063122/ https://www.ncbi.nlm.nih.gov/pubmed/9764574

Ejemplares similares

Effect of eicosapentaenoic acid, protein and amino acids on protein synthesis and degradation in skeletal muscle of cachectic mice
por: Smith, H J, et al.
Publicado: (2004)

Induction of muscle protein degradation by a tumour factor.
por: Lorite, M. J., et al.
Publicado: (1997)

Induction of cachexia in mice by a product isolated from the urine of cachectic cancer patients.
por: Cariuk, P., et al.
Publicado: (1997)

Effect of a cachectic factor on carbohydrate metabolism and attenuation by eicosapentaenoic acid
por: Hussey, H J, et al.
Publicado: (1999)

Decreased NADPH oxidase expression and antioxidant activity in cachectic skeletal muscle
por: Sullivan-Gunn, Melanie J., et al.
Publicado: (2011)

Mechanism of muscle protein degradation in cancer cachexia.
por: Smith, K. L., et al.
Publicado: (1993)

Autophagy is induced in the skeletal muscle of cachectic cancer patients
por: Aversa, Zaira, et al.
Publicado: (2016)

Alteration of serum and urinary lipolytic activity with weight loss in cachectic cancer patients.
por: Groundwater, P., et al.
Publicado: (1990)

Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor (PIF)
por: Lorite, M J, et al.
Publicado: (2001)

Motor protein function in skeletal abdominal muscle of cachectic cancer patients
por: Taskin, Sultan, et al.
Publicado: (2014)

The role of zinc in the anti-tumour and anti-cachectic activity of D-myo-inositol 1,2,6-triphosphate
por: Russell, S T, et al.
Publicado: (2010)

NF-κB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin–proteasome system in skeletal muscle
por: Wyke, S M, et al.
Publicado: (2005)

Inflammatory signalling regulates eccentric contraction‐induced protein synthesis in cachectic skeletal muscle
por: Hardee, Justin P., et al.
Publicado: (2017)

Increased protein degradation and decreased protein synthesis in skeletal muscle during cancer cachexia.
por: Smith, K. L., et al.
Publicado: (1993)

Diet-Induced Gene Expression Changes of Cachectic Muscle, Adipose, and Liver
por: Angelotti, Austin, et al.
Publicado: (2022)

Cleavage of caspases-1, -3, -6, -8 and -9 substrates by proteases in skeletal muscles from mice undergoing cancer cachexia
por: Belizário, J E, et al.
Publicado: (2001)

L-Citrulline Protects Skeletal Muscle Cells from Cachectic Stimuli through an iNOS-Dependent Mechanism
por: Ham, Daniel J., et al.
Publicado: (2015)

Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats
por: Salazar-Degracia, Anna, et al.
Publicado: (2017)

Effects of Aerobic Exercise Training on MyomiRs Expression in Cachectic and Non-Cachectic Cancer Mice
por: Gomes, João Lucas Penteado, et al.
Publicado: (2021)

Analyzing cachectic phenotypes in the muscle and fat body of Drosophila larvae
por: Dark, Callum, et al.
Publicado: (2022)

Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction
por: Kunzke, Thomas, et al.
Publicado: (2019)

Adenosine monophosphate‐activated protein kinase is elevated in human cachectic muscle and prevents cancer‐induced metabolic dysfunction in mice
por: Raun, Steffen H., et al.
Publicado: (2023)

Development of an in-vitro model system to investigate the mechanism of muscle protein catabolism induced by proteolysis-inducing factor
por: Gomes-Marcondes, M C C, et al.
Publicado: (2002)

ERAS: Improving outcome in the cachectic HPB patient
por: van Dijk, David P.J., et al.
Publicado: (2017)

Comment on Sirtuin 1 in skeletal muscle of cachectic tumour-bearing rats
por: Alamdari, Nima, et al.
Publicado: (2012)

Sirtuin 1 in skeletal muscle of cachectic tumour-bearing rats: a role in impaired regeneration?
por: Toledo, Míriam, et al.
Publicado: (2011)

Multiplatform Urinary Metabolomics Profiling to Discriminate Cachectic from Non-Cachectic Colorectal Cancer Patients: Pilot Results from the ColoCare Study
por: Ose, Jennifer, et al.
Publicado: (2019)

Cachectic muscle wasting in acute myeloid leukaemia: a sleeping giant with dire clinical consequences
por: Campelj, Dean G., et al.
Publicado: (2021)

Hypothalamic food intake regulation in a cancer-cachectic mouse model
por: Dwarkasing, Jvalini T., et al.
Publicado: (2013)

DUSP1 promotes muscle atrophy by inhibiting myocyte differentiation in cachectic patients
por: Sui, Xiangyu, et al.
Publicado: (2022)

Pectoralis major muscle atrophy is associated with mitochondrial energy wasting in cachectic patients with gastrointestinal cancer
por: Dolly, Adeline, et al.
Publicado: (2022)

The cachexia score (CASCO): a new tool for staging cachectic cancer patients
por: Argilés, Josep M., et al.
Publicado: (2011)

Effect of a tumour-produced lipid-mobilizing factor on protein synthesis and degradation
por: Islam-Ali, B S, et al.
Publicado: (2001)

Gut microbiota and short‐chain fatty acid alterations in cachectic cancer patients
por: Ubachs, Jorne, et al.
Publicado: (2021)

Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer
por: Silvério, Renata, et al.
Publicado: (2017)

Disruption of pro-oxidant and antioxidant systems with elevated expression of the ubiquitin proteosome system in the cachectic heart muscle of nude mice
por: Hinch, E. C. A., et al.
Publicado: (2013)

Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice
por: van Norren, K, et al.
Publicado: (2009)

Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice
por: van Norren, K, et al.
Publicado: (2009)

The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer
por: Kemik, Ozgur, et al.
Publicado: (2010)

Pharmacokinetics of Drugs in Cachectic Patients: A Systematic Review
por: Trobec, Katja, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_9qq3scos7sa3dq87gqutpjbbup