Establishment of a retinoic acid-resistant human acute promyelocytic leukaemia (APL) model in human granulocyte-macrophage colony-stimulating factor (hGM-CSF) transgenic severe combined immunodeficiency (SCID) mice.

To understand the mechanisms and identify novel approaches to overcoming retinoic acid (RA) resistance in acute promyelocytic leukaemia (APL), we established the first human RA-resistant APL model in severe combined immunodeficiency (SCID) mice. UF-1 cells, an RA-resistant APL cell line established...

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Detalles Bibliográficos
Autores principales: Fukuchi, Y., Kizaki, M., Kinjo, K., Awaya, N., Muto, A., Ito, M., Kawai, Y., Umezawa, A., Hata, J., Ueyama, Y., Ikeda, Y.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063129/
https://www.ncbi.nlm.nih.gov/pubmed/9764578

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