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Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN.
The chromosomal region 10q23-24 is frequently deleted in a number of tumour types, including prostate adenocarcinoma and glioma. A candidate tumour-suppressor gene at 10q23.3, designated PTENor MMAC1, with putative actin-binding and tyrosine phosphatase domains has recently been described. Mutations...
Autores principales: | Gray, I. C., Stewart, L. M., Phillips, S. M., Hamilton, J. A., Gray, N. E., Watson, G. J., Spurr, N. K., Snary, D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group|1
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063186/ https://www.ncbi.nlm.nih.gov/pubmed/9823969 |
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