Wild-type p53-mediated down-modulation of interleukin 15 and interleukin 15 receptors in human rhabdomyosarcoma cells.

We recently reported that rhabdomyosarcoma cell lines express and secrete interleukin 15 (IL-15), a tightly regulated cytokine with IL-2-like activity. To test whether the p53-impaired function that is frequently found in this tumour type could play a role in the IL-15 production, wild-type p53 gene...

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Detalles Bibliográficos
Autores principales: De Giovanni, C., Nanni, P., Sacchi, A., Soddu, S., Manni, I., D'Orazi, G., Bulfone-Paus, S., Pohl, T., Landuzzi, L., Nicoletti, G., Frabetti, F., Rossi, I., Lollini, P. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063235/
https://www.ncbi.nlm.nih.gov/pubmed/9862562

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