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CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer.
Sixty-three patients with extensive-stage small-cell lung cancer were randomized to receive either cyclophosphamide, vincristine, doxorubicin and etoposide (CODE) alone or CODE plus recombinant human granulocyte colony-stimulating factor (rhG-CSF). rhG-CSF administration in support of CODE chemother...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group|1
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063260/ https://www.ncbi.nlm.nih.gov/pubmed/9010043 |
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author | Fukuoka, M. Masuda, N. Negoro, S. Matsui, K. Yana, T. Kudoh, S. Kusunoki, Y. Takada, M. Kawahara, M. Ogawara, M. Kodama, N. Kubota, K. Furuse, K. |
author_facet | Fukuoka, M. Masuda, N. Negoro, S. Matsui, K. Yana, T. Kudoh, S. Kusunoki, Y. Takada, M. Kawahara, M. Ogawara, M. Kodama, N. Kubota, K. Furuse, K. |
author_sort | Fukuoka, M. |
collection | PubMed |
description | Sixty-three patients with extensive-stage small-cell lung cancer were randomized to receive either cyclophosphamide, vincristine, doxorubicin and etoposide (CODE) alone or CODE plus recombinant human granulocyte colony-stimulating factor (rhG-CSF). rhG-CSF administration in support of CODE chemotherapy resulted in increased mean total received dose intensity for all drugs (P = 0.03) with a significant improvement in survival (P = 0.004). |
format | Text |
id | pubmed-2063260 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1997 |
publisher | Nature Publishing Group|1 |
record_format | MEDLINE/PubMed |
spelling | pubmed-20632602009-09-10 CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer. Fukuoka, M. Masuda, N. Negoro, S. Matsui, K. Yana, T. Kudoh, S. Kusunoki, Y. Takada, M. Kawahara, M. Ogawara, M. Kodama, N. Kubota, K. Furuse, K. Br J Cancer Research Article Sixty-three patients with extensive-stage small-cell lung cancer were randomized to receive either cyclophosphamide, vincristine, doxorubicin and etoposide (CODE) alone or CODE plus recombinant human granulocyte colony-stimulating factor (rhG-CSF). rhG-CSF administration in support of CODE chemotherapy resulted in increased mean total received dose intensity for all drugs (P = 0.03) with a significant improvement in survival (P = 0.004). Nature Publishing Group|1 1997 /pmc/articles/PMC2063260/ /pubmed/9010043 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Fukuoka, M. Masuda, N. Negoro, S. Matsui, K. Yana, T. Kudoh, S. Kusunoki, Y. Takada, M. Kawahara, M. Ogawara, M. Kodama, N. Kubota, K. Furuse, K. CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer. |
title | CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer. |
title_full | CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer. |
title_fullStr | CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer. |
title_full_unstemmed | CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer. |
title_short | CODE chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer. |
title_sort | code chemotherapy with and without granulocyte colony-stimulating factor in small-cell lung cancer. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063260/ https://www.ncbi.nlm.nih.gov/pubmed/9010043 |
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