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Genetic changes associated with the acquisition of androgen-independent growth, tumorigenicity and metastatic potential in a prostate cancer model.
Genetic changes underlying the progression of human prostate cancer are incompletely understood. Recently, an experimental model system that resembles human prostate cancer progression was developed based on the serial passage of an androgen-responsive, non-tumorigenic LNCaP prostate cancer cell lin...
Autores principales: | Hyytinen, E. R., Thalmann, G. N., Zhau, H. E., Karhu, R., Kallioniemi, O. P., Chung, L. W., Visakorpi, T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group|1
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063274/ https://www.ncbi.nlm.nih.gov/pubmed/9010025 |
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