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Incorporation of iododeoxyuridine in multicellular glioma spheroids: implications for DNA-targeted radiotherapy using Auger electron emitters.

A promising new treatment for glioma involves Auger electron emitters such as 125I or 123I conjugated to deoxyuridine (IUdR). However, the presence in tumour deposits of non-proliferating cells with clonogenic potential poses a major limitation to this cycle-specific therapy. We have used multicellu...

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Detalles Bibliográficos
Autores principales: Neshasteh-Riz, A., Angerson, W. J., Reeves, J. R., Smith, G., Rampling, R., Mairs, R. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group|1 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063300/
https://www.ncbi.nlm.nih.gov/pubmed/9052399

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