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Mining Predicted Essential Genes of Brugia malayi for Nematode Drug Targets

We report results from the first genome-wide application of a rational drug target selection methodology to a metazoan pathogen genome, the completed draft sequence of Brugia malayi, a parasitic nematode responsible for human lymphatic filariasis. More than 1.5 billion people worldwide are at risk o...

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Detalles Bibliográficos
Autores principales:	Kumar, Sanjay, Chaudhary, Kshitiz, Foster, Jeremy M., Novelli, Jacopo F., Zhang, Yinhua, Wang, Shiliang, Spiro, David, Ghedin, Elodie, Carlow, Clotilde K. S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063515/ https://www.ncbi.nlm.nih.gov/pubmed/18000556 http://dx.doi.org/10.1371/journal.pone.0001189

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