Cargando…

Dynamics of the peroxisomal import cycle of PpPex20p: ubiquitin-dependent localization and regulation

We characterize the peroxin PpPex20p from Pichia pastoris and show its requirement for translocation of PTS2 cargoes into peroxisomes. PpPex20p docks at the peroxisomal membrane and translocates into peroxisomes. Its peroxisomal localization requires the docking peroxin Pex14p but not the peroxins P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Léon, Sébastien, Zhang, Lan, McDonald, W. Hayes, Yates, John, Cregg, James M., Subramani, Suresh
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063535/ https://www.ncbi.nlm.nih.gov/pubmed/16390998 http://dx.doi.org/10.1083/jcb.200508096

Ejemplares similares

Pex22p of Pichia pastoris, Essential for Peroxisomal Matrix Protein Import, Anchors the Ubiquitin-Conjugating Enzyme, Pex4p, on the Peroxisomal Membrane
por: Koller, Antonius, et al.
Publicado: (1999)

PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS
por: Demers, Nicholas D., et al.
Publicado: (2023)

Ubiquitination of the peroxisomal import receptor Pex5p is required for its recycling
por: Platta, Harald W., et al.
Publicado: (2007)

PEX5 and Ubiquitin Dynamics on Mammalian Peroxisome Membranes
por: Brown, Aidan I., et al.
Publicado: (2014)

Recognition and Chaperoning by Pex19, Followed by Trafficking and Membrane Insertion of the Peroxisome Proliferation Protein, Pex11
por: Zientara-Rytter, Katarzyna M., et al.
Publicado: (2022)

TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import
por: Wang, Wei, et al.
Publicado: (2017)

The Structure of the Arabidopsis PEX4-PEX22 Peroxin Complex—Insights Into Ubiquitination at the Peroxisomal Membrane
por: Traver, Melissa S., et al.
Publicado: (2022)

The unique degradation pathway of the PTS2 receptor, Pex7, is dependent on the PTS receptor/coreceptor, Pex5 and Pex20
por: Hagstrom, Danielle, et al.
Publicado: (2014)

Phosphorylation-dependent Pex11p and Fis1p interaction regulates peroxisome division
por: Joshi, Saurabh, et al.
Publicado: (2012)

The Peroxin Pex19p Interacts with Multiple, Integral Membrane Proteins at the Peroxisomal Membrane
por: Snyder, William B., et al.
Publicado: (2000)

Cysteine-specific ubiquitination protects the peroxisomal import receptor Pex5p against proteasomal degradation
por: Schwartzkopff, Benjamin, et al.
Publicado: (2015)

Pex12 Interacts with Pex5 and Pex10 and Acts Downstream of Receptor Docking in Peroxisomal Matrix Protein Import
por: Chang, Chia-Che, et al.
Publicado: (1999)

Involvement of Pex13p in Pex14p Localization and Peroxisomal Targeting Signal 2–dependent Protein Import into Peroxisomes
por: Girzalsky, Wolfgang, et al.
Publicado: (1999)

The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway
por: Matsuzaki, Takashi, et al.
Publicado: (2008)

Interdependence of the Peroxisome-targeting Receptors in Arabidopsis thaliana: PEX7 Facilitates PEX5 Accumulation and Import of PTS1 Cargo into Peroxisomes
por: Ramón, Naxhiely Martínez, et al.
Publicado: (2010)

Membrane Interactions of the Peroxisomal Proteins PEX5 and PEX14
por: Gaussmann, Stefan, et al.
Publicado: (2021)

Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19
por: Emmanouilidis, Leonidas, et al.
Publicado: (2017)

PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins
por: Fang, Yi, et al.
Publicado: (2004)

Yeast pex1 cells contain peroxisomal ghosts that import matrix proteins upon reintroduction of Pex1
por: Knoops, Kèvin, et al.
Publicado: (2015)

A Mechanistic Perspective on PEX1 and PEX6, Two AAA+ Proteins of the Peroxisomal Protein Import Machinery
por: Pedrosa, Ana G., et al.
Publicado: (2019)

Mitotic phosphorylation of Pex14p regulates peroxisomal import machinery
por: Yamashita, Koichiro, et al.
Publicado: (2020)

Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5
por: Galiani, S., et al.
Publicado: (2022)

PEX11 promotes peroxisome division independently of peroxisome metabolism
por: Li, Xiaoling, et al.
Publicado: (2002)

Ubiquitin-conjugating activity by PEX4 is required for efficient protein transport to peroxisomes in Arabidopsis thaliana
por: Mano, Shoji, et al.
Publicado: (2022)

Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes
por: Fischer, Sven, et al.
Publicado: (2023)

The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeast
por: Tower, Robert J., et al.
Publicado: (2011)

PEX16 contributes to peroxisome maintenance by constantly trafficking PEX3 via the ER
por: Aranovich, Alexander, et al.
Publicado: (2014)

The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading
por: Gardner, Brooke M., et al.
Publicado: (2018)

Insights into the Structure and Function of the Pex1/Pex6 AAA-ATPase in Peroxisome Homeostasis
por: Judy, Ryan M., et al.
Publicado: (2022)

Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate
por: Rüttermann, Maximilian, et al.
Publicado: (2023)

The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation
por: Okumoto, Kanji, et al.
Publicado: (2020)

Heimler Syndrome Is Caused by Hypomorphic Mutations in the Peroxisome-Biogenesis Genes PEX1 and PEX6
por: Ratbi, Ilham, et al.
Publicado: (2015)

Elevated growth temperature decreases levels of the PEX5 peroxisome-targeting signal receptor and ameliorates defects of Arabidopsis mutants with an impaired PEX4 ubiquitin-conjugating enzyme
por: Kao, Yun-Ting, et al.
Publicado: (2015)

PEX16: a multifaceted regulator of peroxisome biogenesis
por: Kim, Peter K., et al.
Publicado: (2013)

Peroxisomal protein PEX13 functions in selective autophagy
por: Lee, Ming Y, et al.
Publicado: (2016)

Knockdown of PEX16 Induces Autophagic Degradation of Peroxisomes
por: Wei, Xiaofan, et al.
Publicado: (2021)

The PEX7-Mediated Peroxisomal Import System Is Required for Fungal Development and Pathogenicity in Magnaporthe oryzae
por: Goh, Jaeduk, et al.
Publicado: (2011)

Pex14p Phosphorylation Modulates Import of Citrate Synthase 2 Into Peroxisomes in Saccharomyces cerevisiae
por: Schummer, Andreas, et al.
Publicado: (2020)

Membrane Processing and Steady-State Regulation of the Alternative Peroxisomal Import Receptor Pex9p
por: Rudowitz, Markus, et al.
Publicado: (2020)

De Novo Peroxisome Biogenesis in Penicillium Chrysogenum Is Not Dependent on the Pex11 Family Members or Pex16
por: Opaliński, Łukasz, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_lfk5i97d1ckrrdetl371fs2lho