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Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis

We assessed viable Pax7 (−) (/) (−) mice in 129Sv/J background and observed reduced growth and marked muscle wasting together with a complete absence of functional satellite cells. Acute injury resulted in an extreme deficit in muscle regeneration. However, a small number of regenerated myofibers we...

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Detalles Bibliográficos
Autores principales: Kuang, Shihuan, Chargé, Sophie B., Seale, Patrick, Huh, Michael, Rudnicki, Michael A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063538/
https://www.ncbi.nlm.nih.gov/pubmed/16391000
http://dx.doi.org/10.1083/jcb.200508001