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Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis
We assessed viable Pax7 (−) (/) (−) mice in 129Sv/J background and observed reduced growth and marked muscle wasting together with a complete absence of functional satellite cells. Acute injury resulted in an extreme deficit in muscle regeneration. However, a small number of regenerated myofibers we...
Autores principales: | Kuang, Shihuan, Chargé, Sophie B., Seale, Patrick, Huh, Michael, Rudnicki, Michael A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063538/ https://www.ncbi.nlm.nih.gov/pubmed/16391000 http://dx.doi.org/10.1083/jcb.200508001 |
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