Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation

Morphogenesis of a vascular network requires dynamic vessel growth and regression. To investigate the cellular mechanism underlying this process, we deleted focal adhesion kinase (FAK), a key signaling mediator, in endothelial cells (ECs) using Tie2-Cre mice. Targeted FAK depletion occurred efficien...

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Detalles Bibliográficos
Autores principales: Braren, Rickmer, Hu, Huiqing, Kim, Yung Hae, Beggs, Hilary E., Reichardt, Louis F., Wang, Rong
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063542/
https://www.ncbi.nlm.nih.gov/pubmed/16391003
http://dx.doi.org/10.1083/jcb.200506184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063542/
https://www.ncbi.nlm.nih.gov/pubmed/16391003
http://dx.doi.org/10.1083/jcb.200506184

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