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Focal adhesion size controls tension-dependent recruitment of α-smooth muscle actin to stress fibers

Expression of α-smooth muscle actin (α-SMA) renders fibroblasts highly contractile and hallmarks myofibroblast differentiation. We identify α-SMA as a mechanosensitive protein that is recruited to stress fibers under high tension. Generation of this threshold tension requires the anchoring of stress...

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Detalles Bibliográficos
Autores principales:	Goffin, Jérôme M., Pittet, Philippe, Csucs, Gabor, Lussi, Jost W., Meister, Jean-Jacques, Hinz, Boris
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063555/ https://www.ncbi.nlm.nih.gov/pubmed/16401722 http://dx.doi.org/10.1083/jcb.200506179

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