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Two binding partners cooperate to activate the molecular motor Kinesin-1
The regulation of molecular motors is an important cellular problem, as motility in the absence of cargo results in futile adenosine triphosphate hydrolysis. When not transporting cargo, the microtubule (MT)-based motor Kinesin-1 is kept inactive as a result of a folded conformation that allows auto...
Autores principales: | Blasius, T. Lynne, Cai, Dawen, Jih, Gloria T., Toret, Christopher P., Verhey, Kristen J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063617/ https://www.ncbi.nlm.nih.gov/pubmed/17200414 http://dx.doi.org/10.1083/jcb.200605099 |
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