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The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1

The tensin family member cten (C-terminal tensin like) is an Src homology 2 (SH2) and phosphotyrosine binding domain–containing focal adhesion molecule that may function as a tumor suppressor. However, the mechanism has not been well established. We report that cten binds to another tumor suppressor...

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Detalles Bibliográficos
Autores principales: Liao, Yi-Chun, Si, Lizhen, deVere White, Ralph W., Lo, Su Hao
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063623/
https://www.ncbi.nlm.nih.gov/pubmed/17190795
http://dx.doi.org/10.1083/jcb.200608015