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Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1)

Mammalian oocytes are arrested in prophase of the first meiotic division. Progression into the first meiotic division is driven by an increase in the activity of maturation-promoting factor (MPF). In mouse oocytes, we find that early mitotic inhibitor 1 (Emi1), an inhibitor of the anaphase-promoting...

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Detalles Bibliográficos
Autores principales: Marangos, Petros, Verschuren, Emmy W., Chen, Ruby, Jackson, Peter K., Carroll, John
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063628/
https://www.ncbi.nlm.nih.gov/pubmed/17190794
http://dx.doi.org/10.1083/jcb.200607070