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Shoichiro Tsukita: a life exploring the molecular architecture of the tight junction
On December 11, 2005, Shoichiro Tsukita died at the young age of 52, after 14 months of treatment for cancer. Early in his career, Tsukita succeeded in isolating and purifying the adherens junction with his wife Sachiko, an accomplishment that he followed up with an impressive series of discoveries...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063636/ https://www.ncbi.nlm.nih.gov/pubmed/16449186 http://dx.doi.org/10.1083/jcb.200512163 |
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author | Takeichi, Masatoshi |
author_facet | Takeichi, Masatoshi |
author_sort | Takeichi, Masatoshi |
collection | PubMed |
description | On December 11, 2005, Shoichiro Tsukita died at the young age of 52, after 14 months of treatment for cancer. Early in his career, Tsukita succeeded in isolating and purifying the adherens junction with his wife Sachiko, an accomplishment that he followed up with an impressive series of discoveries of cell adhesion and cytoskeletal molecules, including what may have been his greatest contribution to the field, the identification of occludin and the claudin family of molecules, which were watershed discoveries in the study of the molecular nature of tight junctions. |
format | Text |
id | pubmed-2063636 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-20636362007-11-29 Shoichiro Tsukita: a life exploring the molecular architecture of the tight junction Takeichi, Masatoshi J Cell Biol News On December 11, 2005, Shoichiro Tsukita died at the young age of 52, after 14 months of treatment for cancer. Early in his career, Tsukita succeeded in isolating and purifying the adherens junction with his wife Sachiko, an accomplishment that he followed up with an impressive series of discoveries of cell adhesion and cytoskeletal molecules, including what may have been his greatest contribution to the field, the identification of occludin and the claudin family of molecules, which were watershed discoveries in the study of the molecular nature of tight junctions. The Rockefeller University Press 2006-01-30 /pmc/articles/PMC2063636/ /pubmed/16449186 http://dx.doi.org/10.1083/jcb.200512163 Text en Copyright © 2006, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | News Takeichi, Masatoshi Shoichiro Tsukita: a life exploring the molecular architecture of the tight junction |
title | Shoichiro Tsukita: a life exploring the molecular architecture of the tight junction |
title_full | Shoichiro Tsukita: a life exploring the molecular architecture of the tight junction |
title_fullStr | Shoichiro Tsukita: a life exploring the molecular architecture of the tight junction |
title_full_unstemmed | Shoichiro Tsukita: a life exploring the molecular architecture of the tight junction |
title_short | Shoichiro Tsukita: a life exploring the molecular architecture of the tight junction |
title_sort | shoichiro tsukita: a life exploring the molecular architecture of the tight junction |
topic | News |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063636/ https://www.ncbi.nlm.nih.gov/pubmed/16449186 http://dx.doi.org/10.1083/jcb.200512163 |
work_keys_str_mv | AT takeichimasatoshi shoichirotsukitaalifeexploringthemoleculararchitectureofthetightjunction |