Cargando…

AP-2α: a regulator of EGF receptor signaling and proliferation in skin epidermis

AP-2 transcription factors have been implicated in epidermal biology, but their functional significance has remained elusive. Using conditional knockout technology, we show that AP-2α is essential for governing the balance between growth and differentiation in epidermis. In vivo, epidermis lacking A...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xuan, Bolotin, Diana, Chu, David H., Polak, Lisa, Williams, Trevor, Fuchs, Elaine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063650/
https://www.ncbi.nlm.nih.gov/pubmed/16449191
http://dx.doi.org/10.1083/jcb.200510002