Nuclear actin: to polymerize or not to polymerize

The form and function of actin in the nucleus have been enigmatic for over 30 years. Recently actin has been assigned numerous functional roles in the nucleus, but its form remains a mystery. The intricate relationship between actin form and function in the cytoplasm implies that understanding the s...

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Detalles Bibliográficos
Autores principales: Hofmann, Wilma A., de Lanerolle, Primal
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063669/
https://www.ncbi.nlm.nih.gov/pubmed/16476772
http://dx.doi.org/10.1083/jcb.200601095
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author Hofmann, Wilma A.
de Lanerolle, Primal
author_facet Hofmann, Wilma A.
de Lanerolle, Primal
author_sort Hofmann, Wilma A.
collection PubMed
description The form and function of actin in the nucleus have been enigmatic for over 30 years. Recently actin has been assigned numerous functional roles in the nucleus, but its form remains a mystery. The intricate relationship between actin form and function in the cytoplasm implies that understanding the structural properties of nuclear actin is elementary to fully understanding its function. In this issue, McDonald et al. (p. 541) use fluorescence recovery after photobleaching (FRAP) to tackle the question of whether nuclear actin exists as monomers or polymers.
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spelling pubmed-20636692007-11-29 Nuclear actin: to polymerize or not to polymerize Hofmann, Wilma A. de Lanerolle, Primal J Cell Biol Reviews The form and function of actin in the nucleus have been enigmatic for over 30 years. Recently actin has been assigned numerous functional roles in the nucleus, but its form remains a mystery. The intricate relationship between actin form and function in the cytoplasm implies that understanding the structural properties of nuclear actin is elementary to fully understanding its function. In this issue, McDonald et al. (p. 541) use fluorescence recovery after photobleaching (FRAP) to tackle the question of whether nuclear actin exists as monomers or polymers. The Rockefeller University Press 2006-02-13 /pmc/articles/PMC2063669/ /pubmed/16476772 http://dx.doi.org/10.1083/jcb.200601095 Text en Copyright © 2006, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Reviews
Hofmann, Wilma A.
de Lanerolle, Primal
Nuclear actin: to polymerize or not to polymerize
title Nuclear actin: to polymerize or not to polymerize
title_full Nuclear actin: to polymerize or not to polymerize
title_fullStr Nuclear actin: to polymerize or not to polymerize
title_full_unstemmed Nuclear actin: to polymerize or not to polymerize
title_short Nuclear actin: to polymerize or not to polymerize
title_sort nuclear actin: to polymerize or not to polymerize
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063669/
https://www.ncbi.nlm.nih.gov/pubmed/16476772
http://dx.doi.org/10.1083/jcb.200601095
work_keys_str_mv AT hofmannwilmaa nuclearactintopolymerizeornottopolymerize
AT delanerolleprimal nuclearactintopolymerizeornottopolymerize

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